What are the symptoms of stage 5 kidney disease? Chronic kidney disease stage 5 means that patients have become uremia stage. GFR is less than 15 and serum creatinine is more than 707umol/L. In this stage, there are many toxins which accumulate in the body because kidney fails. The toxins give damage to many other organs or systems such as digestive system, nerve system, heart and so on.
As for digestive system’s damage, patients will feel nausea, vomiting, poor appetite, etc. As for the nerve system, patients may easy fall asleep, fatigue, dizzy, etc. Stage 5 kidney disease can also have anemia, which is caused by the insufficiency of EPO generation. EPO is produced in kidney. When kidney fails, the secretion decreases, the red blood cells can not generate normally, thus causing anemia and patients look pale on face. In turn, kidney failure leads to many toxins in the body, which threaten the life of red blood cells, worsening anemia.
What’s more, high blood pressure or hypertension will also take place in stage 5 of chronic kidney disease.
About 23% to 70% patients with chronic renal glomerular nephritis will suffer from high blood pressure with the disease developing. The more renal function declines, the higher blood pressure will be. In addition, lesion in renal parenchyma and renal tubules can also lead to high blood pressure such as insufficiency of chronic pyelonephritis. Half of them can lead to high blood pressure. High blood pressure or hypertension will in turn damage kidney. High blood pressure makes the heart work harder and, over time, can damage blood vessels throughout the body. If the blood vessels in the kidneys are damaged, they may stop removing wastes and extra fluid from the body. The extra fluid in the blood vessels may then raise blood pressure even more. It's a dangerous cycle.
Pain in the back can also takes place, especially for those with PKD, renal cysts and so on. Other kidney disease patients can also feel painful in back when it is knocked.
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