Kidney damage caused by diabetes is called diabetic nephropathy. We can also say that diabetic nephropathy is the complication of diabetes and diabetic nephropathy is a secondary kidney disease. Many people want to know the pathological mechanism about how diabetes develops into diabetic nephropathy so as to get effective treatment for generally after 10 years, diabetes may lead to diabetic nephropathy. The factors are as follows:
1. high blood pressure
As we know, the most typical feature of diabetes is high blood sugar in the blood. High blood sugar and AGES can lead to the proliferation of mesangial cells, which leads to increased ECM and expands mesangial membrane, thus causing thicken renal glomerular basilar membrane.
2. high blood pressure
High blood pressure has no direct relationship with diabetic nephropathy, but the primary high blood pressure and micro-albumin in urine can accelerate the deterioration of renal function.
3. genetic factor
Genetic factor is also an important element which can influence the occurrence of diabetic nephropathy. Generally, those whose parents have diabetes are more likely to get damage in kidney.
4. abnormal haemodynamics in kidney
Abnormal haemodynamics in kidney is a critical factor which can influence the damage of kidney. When patients are in high blood sugar condition, renal glomerulus are in high perfusion, high filtration condition, which makes the mesangial cells expand. In addition, under big pressure, there will be more protein leaking out, which damages kidney as well.
Even the damage in kidney takes place due to diabetes, we do not need to worry for there is effective treatment. In Shijiazhuang Kidney Disease Hospital, we have immunotherapy, which can treat diabetic nephropathy effectively. In normal condition, our body can recognize and utilize insulin. Insulin has function of using blood sugar; however, when our immune system goes wrong, our body will be failed in recognizing and utilizing insulin. When insulin secreted by pancreas islet can not display their sugar-lowering function, blood sugar accumulates in our body and finally, leading to the increase of blood sugar level.
Therefore, on the basis of above theory, to relieve or control this condition, we need to regulate immune system, which will enable our body to recognize and use insulin. When insulin display their function in our body, blood sugar will be used effectively and consequently, blood sugar level decreases.
Immunotherapy in our hospital can be divided into 6 main steps: immune diagnosis, immune clearance, immune inhibition, immune tolerance, immune adjustment and immune protection. Last but not least, it contains Chinese Medicine, which can repair the damaged kidney function and increase the immune ability, which is quite different from most western medicines. For more information, please consult us online or email us.
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