How to Treat Lupus Nephritis with Immunotherapy
To know how to treat lupus nephritis, we should firstly figure out the pathological mechanism of lupus nephritis. The main cause of this disease is that when the body is infected by lupus cells, abnormal immune response exists continuously and pathogenic autoantibody is produced, as a result, large amount of immune complex, such as C3, IgG, IgM, etc. was generated in the blood, which deposit at the glomerular epithelial cells, thus damaging the normal function of the glomerular epithelial cells. In this case, proteins and red blood cells will leak out through the pores of the basilar membrane, thus causing protein in urine or hematuria in clinic.
It is an autoimmune disease. The regular medications are hormones and immunosuppressive agents, which can indeed diminish the leaking out of protein and red blood cells. However, after infection, protein in urine or blood urine will come into being again. To treat lupus nephritis, the therapy should be based on how it comes into being.
Immunotherapy is created in Eastern Greenland Hospital, which is a combination of Chinese medicine and western medicine can be divided into 6 steps, immune diagnosis, immune clearance, immune blocking, immune tolerance, immune regulation and immune protection.
1. immune diagnosis
After a systematic diagnosis, we can figure out where the immune complex deposits exactly, the amount of immune complex so that doctors can get more scientific diagnosis and arrange better treatment. Without it, we can not know the dosage of medicine. Less dosage can not achieve the treatment effect while too much can also cause damage to the kidney.
2. immune clearance
In immune clearance step, patients with lupus nephritis should clear away the immune complex in the blood, which can supply a cleaner inner environment for the treatment of kidney disease. For patients with SLE, the most proper blood purification method is the plasma exchange. Pay attention that the immune complex we clean is the one in the blood not the one on the kidney.
3. immune blocking
There is still immune complex which deposits onto kidney, which leads to immune response and damage to the kidney cells and tissues. Medicine is used, which can stop the excessive immune response, thus stopping the inflammation response at a rapid speed.
4.immuen tolerance
The fourth one is immune tolerance. After immune blocking, the immune response can be stopped. And the damage to the kidney can be blocked. However, the immune complex still deposit onto the kidney, which leads to a new series of immune response.
5. immune regulation
The fifth one is immune adjustment. In this step, Chinese medicines are applied, which can improve the blood circulation, including micro-blood circulation and dissolve the blood stasis. In this case, the immune complex can be discharged out, and the immune system can be repaired. Note that in this step, the immune complex we clean is the one on the kidney not the one in the blood. Blood purification such as dialysis and plasma exchange can not achieve this. In Eastern Greenland Hospital, we use Chinese Medicine. It can also repair the damaged renal glomerular epithelial cells for it contains herbs and nutritious materials.
6. immune protection
Last but not least, immune protection is applied, in which step, we use medicine which can nourish qi and blood to rebuild the intrinsic immune system. In addition, biochemical cell therapy is also used in clinic such as the transplant of stem cell, which can also help enhance the immunity of lupus nephritis patients. In this way, patients themselves can clear away the immune complex in the blood and kidney, thus treating lupus nephritis from root.
To know how to treat lupus nephritis, we should firstly figure out the pathological mechanism of lupus nephritis. The main cause of this disease is that when the body is infected by lupus cells, abnormal immune response exists continuously and pathogenic autoantibody is produced, as a result, large amount of immune complex, such as C3, IgG, IgM, etc. was generated in the blood, which deposit at the glomerular epithelial cells, thus damaging the normal function of the glomerular epithelial cells. In this case, proteins and red blood cells will leak out through the pores of the basilar membrane, thus causing protein in urine or hematuria in clinic.
It is an autoimmune disease. The regular medications are hormones and immunosuppressive agents, which can indeed diminish the leaking out of protein and red blood cells. However, after infection, protein in urine or blood urine will come into being again. To treat lupus nephritis, the therapy should be based on how it comes into being.
Immunotherapy is created in Eastern Greenland Hospital, which is a combination of Chinese medicine and western medicine can be divided into 6 steps, immune diagnosis, immune clearance, immune blocking, immune tolerance, immune regulation and immune protection.
1. immune diagnosis
After a systematic diagnosis, we can figure out where the immune complex deposits exactly, the amount of immune complex so that doctors can get more scientific diagnosis and arrange better treatment. Without it, we can not know the dosage of medicine. Less dosage can not achieve the treatment effect while too much can also cause damage to the kidney.
2. immune clearance
In immune clearance step, patients with lupus nephritis should clear away the immune complex in the blood, which can supply a cleaner inner environment for the treatment of kidney disease. For patients with SLE, the most proper blood purification method is the plasma exchange. Pay attention that the immune complex we clean is the one in the blood not the one on the kidney.
3. immune blocking
There is still immune complex which deposits onto kidney, which leads to immune response and damage to the kidney cells and tissues. Medicine is used, which can stop the excessive immune response, thus stopping the inflammation response at a rapid speed.
4.immuen tolerance
The fourth one is immune tolerance. After immune blocking, the immune response can be stopped. And the damage to the kidney can be blocked. However, the immune complex still deposit onto the kidney, which leads to a new series of immune response.
5. immune regulation
The fifth one is immune adjustment. In this step, Chinese medicines are applied, which can improve the blood circulation, including micro-blood circulation and dissolve the blood stasis. In this case, the immune complex can be discharged out, and the immune system can be repaired. Note that in this step, the immune complex we clean is the one on the kidney not the one in the blood. Blood purification such as dialysis and plasma exchange can not achieve this. In Eastern Greenland Hospital, we use Chinese Medicine. It can also repair the damaged renal glomerular epithelial cells for it contains herbs and nutritious materials.
6. immune protection
Last but not least, immune protection is applied, in which step, we use medicine which can nourish qi and blood to rebuild the intrinsic immune system. In addition, biochemical cell therapy is also used in clinic such as the transplant of stem cell, which can also help enhance the immunity of lupus nephritis patients. In this way, patients themselves can clear away the immune complex in the blood and kidney, thus treating lupus nephritis from root.
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